One of the biggest "gee whiz" applications for the medical PDA has to be multi-drug interaction checking. It never ceases to amaze my patients when I pull out my Palm m515, tap in their list of drugs, and pull up a cross-referenced list of potential interactions in matter of seconds. The implications for improving patient safety with these applications are huge. Curiously, many physicians are not taking full advantage of the drug interaction features built in to the drug reference programs they utilize every day. There are so many programs available with this capability, that there's really no excuse for any PDA-toting clinician not to use one. Here's a list of the drug interaction checkers currently available: